Bulk L-Arginine Powder, 100 g, Packaging May Vary

Product Information

L-arginine supplementation during pregnancy is typically prescribed and monitored by a healthcare provider for a specific reason, such as preeclampsia or the risk of preeclampsia and intrauterine growth restriction (IUGR) ( 22, 26). Blood-thinning medications: clopidogrel (Plavix), enoxaparin (Lovenox), heparin, warfarin (Coumadin), etc. Researchers studied the effects on forearm blood flow by giving intravenous dextrose 5% infusion of D- and L-arginine to 22 patients with stable coronary artery disease. The subjects also performed a 20-minute treadmill exercise. Results showed that it stimulated an insulin-dependent nitric oxide release to improve coronary vasodilation and subsequent blood flow (x). Sexual Health Abba, K., Sudarsanam, T. D., Grobler, L., and Volmink, J. Nutritional supplements for people being treated for active tuberculosis. Cochrane.Database.Syst.Rev. 2008;(4):CD006086. View abstract. Individuals with clogged arteries can take 28 grams of the supplement in equal increments about 3 to 4 times a day.

Even though L-arginine supplements are generally safe to take, they’re not appropriate for everyone and may interact with commonly prescribed medications. Improving athletic performance: The results of a 2020 study suggest that L-arginine supplements may have a positive effect on aerobic and anaerobic exercise performance.

L-arginine Dosage Levels

There’s some evidence that L-arginine supplements may improve pregnancy outcomes, as well as fetal and maternal health in women from both high- and low-resource areas. Reducing high blood pressure: A 2021 meta-analysis suggests L-arginine can help reduce high blood pressure. This may include women who follow restrictive diets or are experiencing severe nausea and vomiting during pregnancy, rendering them unable to meet demands through dietary intake. Viribay, A., et al. (2020). Effects of arginine supplementation on athletic performance based on energy metabolism: A systematic review and meta-analysis. Research suggests that L-arginine supplements are generally safe for most people, even when taken in high doses for long periods. However, some people may experience side effects like stomach pain and diarrhea when taking more than 9 grams per day ( 1, 9).

L-citrulline is an amino acid that may be used as an alternative to L-arginine when taken as a supplement. How does l-arginine help sexual function? Studies not only show it’s ability to increase penile blood flow for sustained erection, but it may also increase sperm count and motility (x, x). Studies also suggest that it may increase blood flow and promote stimulation to female sexual organs (x). Synthesizing Citrulline Can contribute to belly fat loss thanks to the Nitric Oxide from L-Arginine can contribute to fat burning in the long run Research shows that L-arginine may benefit those with diabetes by improving glucose metabolism and insulin sensitivity ( 13). L-citrulline, a precursor to L-arginine that’s discussed later in this article, may be a better choice for boosting athletic performance. Blood pressure regulation

L-arginine side effects

Lower doses are thought not to be as effective, there is firm evidence that taking l-arginine with maritime pine bark extract, along with other ingredients may improve sexual performance. 7 L-citrulline is another amino acid shown to improve certain aspects of athletic performance in some studies. Bracci, M., Tomasetti, M., Malavolta, M., Bonacucina, V., Mocchegiani, E., and Santarelli, L. L-arginine reduces mercury accumulation in thymus of mercury-exposed mice: role of nitric oxide synthase activity and metallothioneins. Ind.Health 2008;46(6):567-574. View abstract. Two teaspoons (6 grams) delivers a higher dose of L-arginine, which may be appropriate for people looking to improve certain aspects of athletic performance.

L-arginine may also interact negatively with certain lifestyle choices such as smoking and drinking. Besides food, l-arginine is also made into supplements. However, supplements are not standardized or regulated by the United States Food and Drug Administration (FDA). Recommended dosages for the following supplement powders are based on a 2,000-calorie diet without daily values. Before taking any supplement, consult a doctor to confirm safety and avoid unwanted side effects. Because L-arginine is primarily found in animal foods, many L-arginine supplements are not vegetarian. If you’re vegan or vegetarian, look for supplements specifically labeled as suitable for these diets. Camic, C. L., Housh, T. J., Zuniga, J. M., Hendrix, R. C., Mielke, M., Johnson, G. O., and Schmidt, R. J. Effects of arginine-based supplements on the physical working capacity at the fatigue threshold. J Strength.Cond.Res 2010;24(5):1306-1312. View abstract. In addition to the potential benefits listed above, some research suggests that L-arginine supplements may be helpful when used in the following ways:

Nutrition

Brittenden, J., Heys, S. D., Ross, J., Park, K. G., and Eremin, O. Natural cytotoxicity in breast cancer patients receiving neoadjuvant chemotherapy: effects of L-arginine supplementation. Eur.J Surg.Oncol. 1994;20(4):467-472. View abstract. There are several additional areas that researchers are interested in exploring regarding L-arginine and its effects on the human body. Although higher doses are often used in research and clinical settings, it’s recommended that daily dosing of L-arginine be kept under 9 grams per day to avoid potential gastrointestinal side effects, including nausea, diarrhea, and bloating.

Fiorentino, G., et al. (2021). Effects of adding L-arginine orally to standard therapy in patients with COVID-19: A randomized, double-blind, placebo-controlled, parallel-group trial. Results of the first interim analysis. Cassone, Faldetta M., Laurenti, O., Desideri, G., Bravi, M. C., De, Luca O., Marinucci, M. C., De, Mattia G., and Ferri, C. L-arginine infusion decreases plasma total homocysteine concentrations through increased nitric oxide production and decreased oxidative status in Type II diabetic patients. Diabetologia 2002;45(8):1120-1127. View abstract. Amore, A., Gianoglio, B., Ghigo, D., Peruzzi, L., Porcellini, M. G., Bussolino, F., Costamagna, C., Cacace, G., Picciotto, G., Mazzucco, G., and . A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine. Kidney Int. 1995;47(6):1507-1514. View abstract.

When to take l-arginine

Some evidence suggests that arginine may help improve blood flow in the heart’s arteries. It is thought that this may help with clogged arteries, chest pain and in some cases angina or coronary artery disease. In those with erectile dysfunction, research has suggested that supplementing daily with 1.5–5 grams of L-arginine may significantly improve symptoms ( 15, 22).